Angiogenesis and Cancer PDF Print E-mail
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Written by Karel Nunnink   

 

Angiogenesis is a big word for a simple concept: it’s the process through which our bodies create new blood vessels. In normal, healthy individuals, new blood vessels grow only under specific circumstances: as part of the healing process for an injury, for instance, or during pregnancy. Our bodies contain a natural system of checks and balances to regulate the growth of blood vessels, known to scientists as angiogenesis stimulators and inhibitors. “The stimulators act as natural fertilizers to get vessels to grow, and the inhibitors prune back extra vessels when they’re no longer needed.m

Without blood vessels to supply them with the nutrients necessary for expansion, microscopic cancers have nothing to do and nowhere to go. But as cancer cells mutate, they can hijack the body’s system of checks and balances, using angiogenesis stimulators to create the blood supply they need. A microscopic tumor, given a steady influx of blood, can grow to up to 16,000 times its original size in as little as two weeks. And, of course, what goes in must come out; the blood feeding the tumor is circulated back through the body, now bearing cancer cells that can take up residence in distant organs, leading to metastasis. “This is the turnkey step that converts a harmless cancer into a deadly one.

Folkman’s theory was that a growing tumor could be “starved to death,” so to speak, by cutting off its blood supply. Forty years ago, he presented his thesis in the New England Journal of Medicine and was met with skepticism, ridicule and dismissal. Today there are 12 antiangiogenic drugs on the market for cancer treatment, with 26 more in the final stages of human testing and another 100-plus behind them in human trials. Every major pharmaceutical company has an angiogenesis program, and the first FDA-approved antiangiogenic cancer drug, Avastin, is practically a household name.

The Preventive Approach

We know the power of antiangiogenic cancer therapy, the sooner a cancer is treated the more likely a patient is to survive the disease. So why wait until the tumor has a blood supply to call its own? Why not prevent the tumor from ever getting past the microscopic phase? While we have no way to consistently and accurately detect microscopic cancers, we can boost our bodies’ natural ability to produce angiogenesis inhibitors. And we don’t need expensive pharmaceuticals or cutting-edge technology to do it.

Instead, we need red grapes. If you’re not crazy about red grapes, red wine will do the trick. Not a big drinker? Green tea works. If you like curry, you’ll be glad to hear that turmeric can help; if you’re a baker, ready that cinnamon shaker. Strawberries, blackberries, raspberries and blueberries; oranges, grapefruit and lemons; apples and pineapples; soy beans, kale and bok choy; garlic, tomatoes and olive oil—all these common foods are also weapons against the development of cancer. (Oh, and don’t forget dark chocolate. I know I won’t.)

 


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“One of the limitations of antiangiogenic therapy today is that we’re primarily treating very advanced disease, So we started a research program looking at natural sources of angiogenesis inhibitors, and what we discovered is that Mother Nature has laced many foods and beverages with naturally occurring inhibitors.

 

 

Research indicates that 75%-80% of cancers are caused in part by environmental factors, and about 30% of those are related to what you eat. News articles tell us that diets rich in red meat can result in an increased risk of prostate cancer, and for some time it was believed that consumption of soy increased women’s breast cancer risk , it might have to do with most Soybeans are now genetically modified.

And it’s not just food and drink. We can also “mine our medicine cabinet, in search of common medications that inhibit angiogenesis, such as aspirin. If you think we’re already aware of everything our boring old over-the-counter drugs can do, think again: in a recently published 30-year study of almost 5,000 women, aspirin was shown to reduce the risk of breast cancer recurrence by a whopping 71%. As US News and World Report’s Dr. Bernadine Healy drily quipped, “Were these aspirin tablets a hot new biotech drug, we would be popping champagne right now.”

To get the most out of the Chart, make sure these foods are Organic, thereby avoiding pesticides and GMOs.

live long and strong.

karel.

Source, stand up to Cancer.

 

 

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